Imaging Bacterial Pathogens in Action

Across Scales, from Proteins to Patient

In the research group of Gregor Weiss at the University of Zürich, we aim to unravel the lifecycle of bacterial pathogens through an integrative approach, combining infection biology with advanced structural biology techniques. In collaboration with clinical partners, we develop cryo-electron tomography workflows for biomedical imaging. These innovative methods enable us to dissect the molecular basis of diseases directly in patient-derived samples.

Our Techniques

Functional Assays

Light Microscopy

Cryo-Focused Ion Beam Milling

Cryo-Electron Tomography

Research

Decoding Bacterial Pathogens:
Multiscale Insights into Disease Mechanims

Integrative Multiscale Approach

Urinary Tract Infections (UTIs)

Bacterial Multi-Cellularity

Clinical Cryo-Electron Microscopy

Funding